Infants Exposed To Second Hand Smoke At Imminent Risk Of Lung Cancer As Adults



Those infants that have faced exposure to second hand cigarette smoke are more prone to developing lung cancer when they become adults, even when they would never take to smoking.

The outcome of the study was printed in the journal of the American Association for Cancer Research, ‘Cancer Epidemiology, Biomarker & Prevention’ in the December edition that laid particular focus on tobacco.

second hand smokeDuring the present year itself, greater than 2, 19, 000 U.S. citizens would be detected having lung cancer; with nearly 1, 59, 000 fatalities and counting, some of whom might not have ever smoked during their lifetime.

Studies done till date have revealed that those adults being exposed to second hand smoke have had damaging effects on their health, however information is inadequate on the risk one faces of contracting lung cancer in case of children who had second hand smoke exposure.

This study stands out in comparison to several other preceding studies due to the fact that it was performed in two self-determining groups and involved a molecular evaluation of gene variants of natural immunity – the MBL2 gene or mannose binding lection-2 gene. The MBL2 gene has been observed to have an effect on the vulnerability to respiratory conditions.

Curtis C. Harris, M.D., the chief of the Laboratory of Human Carcinogenesis, NCI and associates gathered data on second hand smoke history among both the sexes during the in-progress study of the National Cancer Institute-Maryland Lung Cancer that took into consideration 624 cases and 348 controls. They employed DNA to genotype the MBL2 gene. Then for purposes of drawing a comparison, Harris, Ping Yang, M.D., Ph.D., professor of epidemiology from the Mayo Clinic, Rochester, Minn., and associates utilised outcomes taken from a study conducted by the Mayo Clinic taken involved 461 never smoked candidates; 172 cases and 289 controls.

Harris and associates were able to find a link in between infancy exposure to second hand cigarette smoke and a heightened risk of developing lung cancer during adulthood. Moreover, MBL2 activity was linked to an even greater risk in those that faced exposure to second hand smoke during infancy.

On the basis of the outcome of this study, Harris has concluded that infants must be kept away from exposure to second hand smoke because of the long-standing health hazards they would have to face as adults. He further mentioned that these outcomes warranted additional research in a larger-scaled populace.

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